HATU (O-(7-Aza-1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate), Novabiochem®

Supplier: Novabiochem (Merck biosciences)
Danger

Synonyms: 1-[Bis(dimethylamino)methylene]-1H-1,2,3-triazolo[4,5-b]pyridinium 3-oxide, hexafluorophosphateHATU

NOVA8.51013.0500EA 1130 EUR
NOVA8.51013.0500 01-62-0041-25 NOVA8.51013.1000 8.51013.0100
HATU (O-(7-Aza-1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate), Novabiochem®
HATU (O-(7-Aza-1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate)

A highly efficient coupling reagent for solid and solution phase peptide synthesis.


In comparative studies HATU has been found to give better coupling yields with less enantiomerization that HBTU, TBTU or PyBOP® [1-3]. It is particularly effective at coupling to N-alkyl amines where other coupling reagents give poor yields and is the preferred reagent for loading resins bearing secondary amino groups.

Formula: C₁₀H₁₅F₆N₆OP
MW: 380.2 g/mol
Melting Pt: 186 °C
Storage Temperature: Refrigerator
MDL Number: MFCD00274639
CAS Number: 148893-10-1

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