HATU (O-(7-Aza-1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate), Novabiochem®

Supplier: Novabiochem (Merck biosciences)

Synonyms: 1-[Bis(dimethylamino)methylene]-1H-1,2,3-triazolo[4,5-b]pyridinium 3-oxide, hexafluorophosphateHATU

01-62-0041-25EA 347 EUR
01-62-0041-25 8.51013.0100 NOVA8.51013.1000 NOVA8.51013.0500
HATU (O-(7-Aza-1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate), Novabiochem®
HATU (O-(7-Aza-1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate)

A highly efficient coupling reagent for solid and solution phase peptide synthesis.

In comparative studies HATU has been found to give better coupling yields with less enantiomerization that HBTU, TBTU or PyBOP® [1-3]. It is particularly effective at coupling to N-alkyl amines where other coupling reagents give poor yields and is the preferred reagent for loading resins bearing secondary amino groups.

Formula: C₁₀H₁₅F₆N₆OP
MW: 380.2 g/mol
Melting Pt: 186 °C
Storage Temperature: Refrigerator
MDL Number: MFCD00274639
CAS Number: 148893-10-1

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