HATU (O-(7-Aza-1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate), Novabiochem®
Supplier: Novabiochem (Merck biosciences)
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Danger
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Synonyms:
1-[Bis(dimethylamino)methylene]-1H-1,2,3-triazolo[4,5-b]pyridinium 3-oxide, hexafluorophosphate
, HATU
NOVA8.51013.0500EA
1220
EUR
NOVA8.51013.0500
01-62-0041-25
NOVA8.51013.1000
8.51013.0100
HATU (O-(7-Aza-1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate), Novabiochem®
HATU (O-(7-Aza-1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate)
A highly efficient coupling reagent for solid and solution phase peptide synthesis.
In comparative studies HATU has been found to give better coupling yields with less enantiomerization that HBTU, TBTU or PyBOP® [1-3]. It is particularly effective at coupling to N-alkyl amines where other coupling reagents give poor yields and is the preferred reagent for loading resins bearing secondary amino groups.
Formula:
C₁₀H₁₅F₆N₆OP MW: 380.2 g/mol Melting Pt: 186 °C Storage Temperature: Refrigerator |
MDL Number:
MFCD00274639 CAS Number: 148893-10-1 |
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