Imprimer

Anti-MMP2 Rabbit Polyclonal Antibody

Fournisseur: Thermo Fisher Scientific
PIEAPA116667EA 0 EUR
PIEAPA116667
Anti-MMP2 Rabbit Polyclonal Antibody
Anticorps
In Western Blot, bands can be seen at approximately 72kDa (proform) and 62kDa (active form). Antigen retrieval is not required for IHC. Suggested positive control: Injured rat nerve lysate. Loss of negative growth regulation and high invasive potential are neoplastic traits often associated with abnormal expression of matrix matalloproteinases. MMP-2, the signalling mechanism for cells to begin migration, triggers the movement when it splits laminin-5 and exposes and integrin-binding site on this component of epithelial basement membrane. The changed form of laminin was found in tumors and in tissues being altered. The activated form of MMP2, however, is not found in benign tumors. Thus detection of the enzyme is a possible early indicator of tumor activity.

Type: Primary
Antigen: MMP2
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Rat, Mouse, Human, Chicken
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