Keep my session open?
Ending In 
The session is expired
Votre session a expiré. Pour votre sécurité, nous vous avons déconnecté.
Voulez-vous vous connecter à nouveau?

Anti-FXR Rabbit Polyclonal Antibody

Fournisseur: Thermo Scientific
Suggested positive control: HeLa nuclear extract. The steroid receptor superfamily acts through direct association with DNA sequences known as hormone response elements (HREs) and bind DNA as either homo- or heterodimers. The promiscuous mediator of heterodimerization, RXR, is the receptor for 9-cis retinoic acid, and dimerizes with VDR, TR, PPAR, as well as several novel receptors including LXR (also referred to as RLD-1) and FXR. FXR and LXR fall into a category of proteins termed orphan receptors because of their lack of a defined function, and in the case of LXR, the lack of a defined ligand. FXR has been shown to bind a class of lipid molecules called farnesoids. LXR/RXR heterodimers have highest affinity for DR-4 DNA elements while FXR/RXR heterodimers bind IR-1 elements. Both LXR/RXR and FXR/RXR heterodimers retain their responsiveness to 9-cis retinoic acid.

Type: Primary
Antigen: FXR
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Isotype: IgG
Reactivity: Human



Développer tout / Réduire tout
Taille Cdt Numéro de catalogue VWR Quantité
100 µL 100 µl PIEAPA116822 Blocked
Blocked Ce produit a été bloqué par votre organisation. Contacter votre service d'achat pour plus d'informations.
Générer des étiquettes code barres Format des étiquettes barre-code: 
Créer une page catalogue sous forme pdf


Symbole antigène FXR
Nom de l'antigène Nuclear Receptor Subfamily 1 Group H Member 4
Réactivité Human
Conjugaison Unconjugated
Clonalité Polyclonal
Type d' Anticorps Primary
Hôte Rabbit
Isotype IgG
Western blot Yes
ImmunoFluorescence Yes
Antigen synonyms Retinoid X receptor-interacting protein 14, Bile acid receptor, RXR-interacting protein 14, Farnesol receptor HRR-1, Farnesoid X-activated receptor
Gene ID 9971
Mesures de concentration 5.7 mg/ml
Immunogen Synthetic peptide made to the C-terminus of human FXR.
Purification Antigen affinity chromatography
Form Liquid
Storage buffer tris glycine, 0.15M NaCl, 0.05% sodium azide
Température de stockage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping temperature Ice
Enter Details

Select the article for which you are looking for Certificate

Indiquez le numéro de lot. Ce champ est obligatoire. ( Si lot inconnu, mettre un "x" )

Enter Certificate Details

Enter the Lot number:

Choose from recent batch/lot numbers:

Review & Compare Alternatives
We found alternative products that can save you up to  per item-unit.  To compare product details, select up to 3 alternatives below and click Compare Selected. To add items to your basket, enter a quantity and click Add to Basket.

Original Product:

Description Numéro de catalogue Availability Unité Votre prix Prix par Quantité