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Anti-CRYAB Rabbit Polyclonal Antibody

Fournisseur: Thermo Scientific
This Crystallin AB antibody is useful for Western blot analysis, where a band is seen at ~20 kDa. There is also a band of greater intensity at ~40 kDa that may be an aggregated heteromeric complex. CryAB aggregates with homologous proteins, including CryAA and the small heat shock protein HSP28, to form large heteromeric complexes.Suggested positive control: human and mouse skeletal muscle lysate, human skeletal muscle protein, antigen standard for HSPB1 (transient overexpression lysate), mouse skeletal muscle protein. Crystallin AB (CryAB) is a developmentally regulated small heat shock protein known to protect cells from stress damage. It may also play an important role in the Golgi reorganization during cell division. CryAB is known to be associated with a number of neurodegenerative pathologies such as Alzheimer disease amd multiple sclerosis. As well, it has been found to be expressed in breast tumors of patients with shorter survival, suggesting that it may be a useful marker in identifying aggressive breast cancer.

Type: Primary
Antigen: CRYAB
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse




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Taille Cdt Numéro de catalogue VWR Quantité
100 µL 100 µl PIEAPA116950 Blocked
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SPÉCIFICATIONS

Symbole antigène CRYAB
Nom de l'antigène Crystallin Alpha B
Réactivité Mouse, Human
Conjugaison Unconjugated
Clonalité Polyclonal
Type d' Anticorps Primary
Hôte Rabbit
Isotype IgG
Western blot Yes
ImmunoFluorescence Yes
Antigen synonyms Heat-shock protein beta-5 antibod, Rosenthal fiber componet antibody, Alpha crystallin B chain antibody, Alpha (B)-crystallin antibody, CryAB antibody
Gene ID 1410, 12955
Mesures de concentration 1.08 mg/ml
Immunogen Synthetic peptide between amino acids 70-140 of the human Crystallin AB protein.
Purification Antigen affinity chromatography
Form Liquid
Storage buffer tris citrate, 0.1% sodium azide, pH 7-8
Température de stockage 4° C, do not freeze
Shipping temperature Ice
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