Concanamycin A (from Streptomyces species) ≥98% (by HPLC)Leverancier: Enzo Life Sciences
White to off-white solid (sub-milligram quantities will appear as clear film)
- Isolated from Streptomyces sp.
Antibiotic. More potent and specific H+-ATPase inhibitor than bafilomycin A1. Inhibits acidification of organelles such as lysosomes and the Golgi apparatus. Blocks cell surface expression of viral glycoproteins without affecting their synthesis. Exhibits cytotoxic effects in a number of cell lines in a cell viability assay. Induces nitric oxide (NO) production. Inhibits Autophagy.
Soluble in methanol, DMSO or acetonitrile, insoluble in water
Verpakking: Shipping temperature: Ambient